What is significance of "focal sclerosing adenosis" in patient with history of breast cancer?

I am a 50-something female with history of left breast cancer (chemotherapy, mastectomy and radiation). A recent ultrasound of my right breast showed a hypoechoic area with shadowing. A core needle biopsy of this area was taken and the report is as follows: "Skin and benign breast tissue with focal sclerosing adenosis with associated microcalcifications." What is the probability that sclerosing adenosis can either mask a malignancy or later develop into one? What follow-up testing or treatment, if any, should I consider?

[PaulMD]

Hi there.

I understand you concern.  This finding on a core biopsy signifies a benign condition, however if there are other characteristics of the breast nodule that will point out to a possible malignancy (like irregular gritty borders, associated skin dimpling, hard and fixed nodule) then the doctor might have to do a larger biopsy like an excision biopsy.  The fact that you had left breast cancer already makes you at risk of developing another breast cancer at the right, and that this finding of sclerosing adenosis may not add to that risk significantly.  I suggest that you continue surveillance with your doctor and that  to discuss with him or her if he's comfortable with the core needle biopsy results.  Regards and God bless.