Breast Cancer Expert Forum
brain metastases from breast cancer treatment/chemotherapy options
About This Forum:

Questions posted in the Breast Cancer Forum are answered by medical professionals and experts. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Avatar universal
brain metastases from breast cancer treatment/chemotherapy options
My sister (47) was diagnosed with breast cancer (T3, ER+, PR+, HER2-) 4 years ago. She had radiotherapy, followed by mastectomy+radiotherapy and chemo with anthracycline, followed by tamoxifen.
October 2007 she was diagnosed with brain metastases (not operable). She was treated with radiotherapy and temodar, which initially had some effect, but then in July 2007 the metastases progressed and her left leg and arm were paralyzed.
She is currently taking CCNU (she had her second treatment a few days ago) and several natural supplements, including Boswellia Serrata (4,200 mg/day; CoQ10, melatonin, bromelain, low fat cottage cheese and flax oil and seeds) and she is on a low fat diet.  However, no much improvement has been noticed.
I would appreciate any advice/suggestion about treatments of brain metastases that could be relevant to my sister's case. What do you think about using xeloda, faslodex, letrosole (femara), or insulin potentiation therapy in the treatment of brain metastases from breast cancer?
It seems that a major issue is whether the drug crosses the blood brain barrier. However, it is known that in case of brain tumor/metastases the integrity of the blood brain barrier is compromised?
Discussion is closed
Cancel
1 Answers
Page 1 of 1
242527 tn?1292452740
Dear winter09:  Brain metastasis can be a difficult problem to treat.  Without evaluation, it is impossible for us to speculate on the specifics of your sister's situation.  You might consider an opinion from a brain tumor specialist at a large center if this is a possibility.
Discussion is closed
Cancel
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
RSS Expert Activity
233488 tn?1310696703
Blank
Marathon Running Done Over Many Yea...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
233488 tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
748543 tn?1463449675
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank