Dear beezus, Microcalcifications are small calcium deposits found within the breast tissue. Calcifications in themselves are not a problem, the concern is what they could be clustering around. Further evaluation such as biopsy is recommended based on the suspicious character of the calcifications (clustered, uneven borders), not solely because of the presence of calcifications. The only way to be sure of what this is, is to biopsy. Without details of your situation, or seeing the mammogram the determination for getting the biopsy now or waiting to see if there are changes* in the mammogram aren't able to be made.
* changes meaning staying the same or changing shape - these don't just go away.
In my own experience, I had to see a few surgeons before I found one who did the procedure (often) and suggested it first as how he would approach the calcifications I had. It was done, and my experience with it, though not what I would call pleasant, was easier to recover from than an open biopsy. It's less invasive and doesn't leave a scar line.
Core biopsy results are considered to be quite reliable, but there are times when an excisional biopsy may be recommended after it. That's another whole kettle of fish.
Hopefully the radiologist told you that about 80% of the time, biopsies for calcifications are negative for cancer.
Good luck with your decisions, and hope that all turns out well.
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