breast cancer

[salg]

My recent open excisional biopsy results are as follows:
Atypical lobular hyperplasia
Atypical ductual hyperplasia
Fibrocystic changes, including radial scar, florid epithelial hypersplsia and fibroadenoma
mutitple levels examined. An E-Cadherin stain shows variable reactivity

I am a 59 women who has been given different answers to the question "What are my risk of Breast Cancer"? I am being checked every six months, and now am going to have an MRI with contrast next month. I am scared to death. Of course I do not understand the difference in point of view from surgeon and Gynocologist. I am presently still taking a small dose of estrogen .0375 with support of doctors. I had a complete hysterectomy at age 50.

Please help

[BhumikaMD]

Hi,

Atypical ductal hyperplasia is not cancer nor is it a pre-cancerous lesion. But it does mean that the individual is predisposed to increased risk of cancer.

Atypical lobular hyperplasia has high chances of developing into cancer in the future. The exact chances cannot be predicted and vary with a number of factors.

For you to understand it - this means that there is an area (focal) from the duct of the breast (ductal) of an increased number of cells than usual (hyperplasia) that look different than normal breast tissue (atypical).

Tamoxifen is known to decrease the risk of developing cancer in the future in patients with Atypical lobular hyperplasia.

Talk to your oncologist in detail about this and clear out any doubts that you have.

It would be best to follow the management plan as advised by your specialist.

Let us know if you have any more doubts.

Regards.

[sonu78]

Hi,
There are lot of predictors that are taken into account to consider a person into any risk groups. These  factors are based on family history, individual's personal and lifestyle history.
It would be better if you can meet the surgeon and discuss about your pathology report in detail.