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conflicting reports ER Postive and ER Negative
Recently had a breast biopsy and then a mastectomy, both pathology reports stated I was ER POSITIVE.   First oncologist visit did the Adjuvant Online tool which said hormonal therapy was the best benefit with only a 2% benefit of having chemo.  He did suggest I might want to have the Oncotype DX test which I did.   Oncotype DX results indicate I am ER NEGATIVE and now chemo is my only option.   What do you believe?  Has anyone experienced this before?  
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25201 tn?1255584436
I'm not quite sure why the conflicting ER reports. Unless you had positive lymph nodes I would think the 2% benefit would not change just because the ER was different. It would only mean that you would derive any benefit from Hormone Therapy. I would ask if either the Path. or Onco be re-checked to be sure about the + vs - for Estrogen so that you would not skip the benefit from Tamoxifen. I would feel more comfortable if there was some agreement. Keep us posted if you get any additional information.  Regards ....
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