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Breast Cancer (Expert Forum)
feet and ankle swelling
Questions posted in the Breast Cancer Forum are answered by medical professionals from The Cleveland Clinic. Topics include Breast Biopsy, Chemotherapy, Hormone Therapy, Lumps, Lumpectomy, Lymph node dissection, Lymphedema, Mammograms, Mastectomy, Radiation Therapy, Reconstruction, Self Breast Exam, and Surgery.
feet and ankle swelling
by conn480, Jul 30, 2004 12:00AM
I had ductal (found on mammogram) and lobular cancer (not found on mammogram) in the right breast. Due to the likelyhood of the lobular showing up in the other breast, I opted for a bilateral mastectomy with immediate reconstruction. The pathology report from the surgery showed that the lobular cancer was already in the left breast. I had 17 nodes removed and all were clear and the largest tumor was just over 1cm. During chemo my periods stopped and they have not returned. I finished chemo at the end of December and went on tamoxifen in January. After starting the tamoxifen, I started getting severe night sweats and hot flashes. My onc put me on Paxil CR which has helped. At the beginning of May I started having pain and weakness in my legs to the point that I had a hard time going up and down my basement stairs. Bood clots were ruled out by ultrasound. He took me off of tamoxifen and put me on arimedex. The pain in my legs went away within a couple of weeks, but then I started retaining water in my feet, ankles, and calves so severe that I have a hard time wearing shoes. Liver and kidney levels are fine and I had an echocardiogram which was normal. He has put me on diruetics which has helped. Two weeks ago he had me stop taking the arimedex. My feet are the closest to normal now than they have been in a long time. Could the arimedex be causing this swelling? If I am having side effects from both tamoxifen and arimedex what are my options? I don't want the cancer to return, but I need to be able to walk. My onc is just as frustrated as I am.
Doctor's Answer
by CCF-RN,MSN-JS, Jul 30, 2004 12:00AM
Dear conn480, Swelling has been noted as an uncommon side effect of Arimidex. In regard to options, decisions are based on risks and benefits for the individual. The risks (side effects) of the medication need to be weighed against the benefits.
Member Comments (2)
by susan m k, Jul 31, 2004 12:00AM
If your periods have stopped permanently - and I believe there is a blood test to determine this, Femara may be a possibility. I had a similar problem with Tamoxifin (tamoxifen) (all joints sore with ankle joints swollen) and was put on Femara about six months ago. My joints are still sore, sometimes I can barely sign my name. I just turned 50 and up until very recently was very active. However, it is worth a try? Good luck, Susan
by ztt, May 25, 2008 03:48PM
A related discussion, Breast cancer and swollen feet when traveling was started.
