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hypoechoic lesions in liver after breast cancer chemo
my mom has got a spread in bone after being diagnosed with breast cancer.. she finished with her 6 rounds of chemotherapy and she has responded very well.. n the doc himself was impressed with the response.. but when she did her sonography and she there is sumthin called as hypoechoic lesions in liver which is less than 2 cm in size.. can these be carcinoma or secondary spread in the organs?? or just a fatty infiltration?? please let me know as i m very worried... is the good response then of no importance??
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Hi,
Inquire from the doctor her risk of getting metastasis to the liver. There are some features of the tumor such as hormonal receptors (sometimes called ER PR estrogen and progesterone receptors) and HER-2 (human epidermal receptor) positivity, which will increase the risk of getting lung and liver disease. The chances of getting fat bodies (if mom was obese before the diagnosis of cancer) should also be estimated. Based on a risk assessment, subsequent imaging (if needed) would be recommended. Your doctor may advise a CT scan or an MRI. If fat is suspect - the MRI would have an advantage to the CT is separating fat from tumor.
Bone metastasis is common, but there is no clear way of measuring chemotherapy response for bone - only the absence of progression would herald the treatment is working. So, it is hard to use the previous experience of a "good response" (which probably meant improvement of symptoms or improvement in some novel urine tests on bone metabolism)  to think that the liver lesion is likely not malignant.
Hypoechoic lesions are generally solid, and hence metastasis is indeed a strong possibility. The presence of a "halo sign" increases the risk.
IT would be best to discuss the chances of the finding  being malignant with your doctor.
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