leg swelling

[booklady]

I have been on Tamoxifen for 6 months after completing 4 rounds of  AC and 37 rad treatments.  So far, the only side effects of the Tamoxifen have been hot flashes and some leg cramps.  About 3 days ago I started to experience leg swelling around my ankles and shins.  It is not very severe and seems to be like edema, which I experienced many years ago when I was pregnant.  I can push down on my shins and leave finger impressions for a short while.  Is this type of swelling associated with Tamoxifen?  What should I do?  Would exercising be okay? Should I increase my water consumption?  I have tried elevating my legs above my heart and the swelling goes down until I am up again.  Thanks for your help.

[CCF-RN,MSN-rf]

Dear booklady:  Swelling is a common (experience by at least 30% of women) side effect of tamoxifen.  As long as it is as you describe, it is safe to go about your activities.  You should let your doctor know next you speak.  If you experience pain on one leg, redness or heat, and swelling on one side, you should let your doctor know immediately.  You may learn more about tamoxifen and its side effects by logging on to www.chemocare.com.  Here is the link to tamoxifen - http://www.chemocare.com/bio/bio.sps?iBiographyID=7951

[surgeon]

what you describe is indeed edema, which can have many causes. So you need to let your doctors know; the causes can be anywhere from inconsequential, to serious (heart and kidney problems for example, or even blood clots in your legs.) It may well turn out to be pretty simple, and respond to such measures as taking diuretics, or wearing support hose, or reducing salt intake (not increasing water intake!). But it needs to be evaluated. Don't delay getting in touch with your doctors!