BREAST CANCER EXPERT FORUM
need help understanding pathology report

need help understanding pathology report

help with interpretation of path report

as follows:

Right breast
Infiltrating ductal carcinoma (2.1) grade 3 located in the upper outer quadrant with peritumorial lymphatic invasion. and extending to 1mm from the deep margin and 2mm from the anterior magin.

Dutal carcinoma in situ focally extratumorial ( primarily localized to the main tumor mass with separate focus in the inner lower quadrant) high grade, located 5mm from the closest deep margin.

er, pr positive  her-2 negative sentinel nodes negative.

Not understanding statement peritumorial lymphatic invasion... confused is there or is there not lymph node invasion?  How does this differ from sentinel node?

I had changed my mind from original plan for lumpectomy and chose bilateral mastectomy with reconstruction.  Left breast prophlactic.  I am assuming this was a wise choice in the end due to the unexpected dx. of DCIS in addition to the known tumor prior to surgery.   thanks.  
Related Discussions
242527_tn?1292452740
Dear chancleta:  The pathology report indicates that there is an invasive component (infiltrating ductal carcinoma) and a non-invasive component (ductal carcinoma in situ) to your breast cancer. It is the invasive part that will dictate most of the treatment recommendations.   Peritumoral lymphatic invasion means that there was evidence of invasion of cancer cells in the lymphatic vessels around the tumor.  It is not the same thing as a positive lymph node.  This finding sometimes indicates that there is a higher chance of cancer spreading to the lymph nodes , although it appears that in your case the sentinel lymph nodes were not involved. Being ER and PR positive suggests that this is a hormone sensitive cancer that may benefit from an anti-hormonal treatment. You should discuss the pathology findings with you physician including what it means in terms of further treatment recommendations.
2 Comments
Blank
Avatar_n_tn
Thank  you for the info.
I am 6 days post surgery.  Surgeon left for vacation  the day I was released from the hospital and will not return until next week at which time I would assume she will refer me to an onocologist.
All I have been told by Surgeon and PCP is that chemo will be require due to the grade 3 and my age.
I would not have know anything more execpt for obtaining a copy of my report.  
I am premenopausal/ perimenopausal ( in my 40's)  so from what I gather the chemo will put me into menopause.  
Will the grade 3 require a more agressive chemo or is that insignificant.
My mother also had BC at the same age as myself and passed away 8 yrs ago .... 17yrs. post diagnosis from brain mets she  initially had mastectomy, then radiation, chemo, tamoxifen.  I had the genetic testing done but it was negative.
I also have 4 daughters so my concerns are primarily that they gain as much info knowledge as possible.
Blank
Continue discussion Blank
Go
MedHelp Health Answers
Submit
Blank
Weight Tracker
Reach your weight goal faster
Start Tracking Now
RSS Expert Activity
1741471_tn?1336957856
Blank
LIVE WEBINAR TOMORROW!-SUPER BODY, ... Blank
May 22 by Michael Gonzalez-WallaceBlank
2126606_tn?1335910182
Blank
Fibromyalgia Awareness
May 11 by Clare Waismann Kavin, RASBlank
2126606_tn?1335910182
Blank
Opioid-induced hyperalgesia reduces...
May 03 by Clare Waismann Kavin, RASBlank