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Dear Pooker6668: TamoxifenTamoxifen Tamoxifen citrate is a selectiveSelective mutism Selective mutism - resourcesestrogenHormone replacement therapy receptor modulator, meaning that it targets estrogen in the breast independent of ovarian production of estrogen. However, if you have had your ovaries removed, then you would be postmenopausal and could possibly take an aromatase inhibitor instead of tamoxifen. Either way, if your breast cancer is hormone receptor positive, then hormone therapy would likely be recommended as the body does produce estrogen outside of the ovaries. You should discuss with your doctor what drug might be best for you.