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I was told by my lactation consultant that the breast is constantly producing milk. So I assume that even if the baby takes an ounce, it will not weigh exactly an ounce less since it is producing more milk as the baby nurses.
However, I can say, based on my personal experiences, that the breasts always felt much lighter after expressing milk.
It is impossible to really calculate how much you nurse in a session. YOu can really only go by how satiated the baby is.