My father ,55 years old, found by himself a enlarged lymph node in his left neck one month ago.He feels well without any active systemic or localizing symptoms . His past medical history was negative.
On physical exam, there is a palpable firm nodes measuring 2-3 cm in the lower left cervical The remainder of his physical examination was negative.
Fine-needle aspiration (FNA) biopsy said metastatic squamous cancer.
Further workup included a computerized tomography (CT) scan of the chest, abdomen, and pelvis, which confirmed the left supraclavicular and also showed another enlarged lymph node (2-3cm) in the upper mediastinum. Ear, nose, and throat evaluation revealed no evident primary lesion on fiberoptic endoscopy.Upper and lower endoscopies of the gastrointestinal (GI) tract were negative.
Positron emission tomography (PET) scanning revealed uptake in the lower left neck, upper mediastinum, but nowhere else.
Would you please help me know what's most possible problem is? Is it lung caner? What's the possible treatment?
Is it possible lymphoma? What's the survival time for this lung caner? Sorry about so many questions, I'm really worried about my dad.
Hi. Cancer metastasis to the left cervical lymph node in a male most commonly comes from cancers of the head and neck or the lungs. Lymphoma could also present with neck node lesions. These areas have been extensively examined by CT, PET and endoscopy, and yet no primary lesion was located. The next step is to do special stains (e.g. immunostaining) on the biopsy sample to help determine its tissue of origin. However, the biopsy should be repeated, because immunostaining cannot be performed on an FNA sample (the amount of tissue is too small). An excision biopsy of that cervical node should ideally be done. Certain stains like cytokeratin and Leukocyte Common Antigen (LCA) can differentiate between lymphoma, head and neck or lung cancers.
At this point, it may be premature to discuss survival and prognosis because these would really depend on what kind of cancer your father has. I can understand your anxiety and concern, but for now, the best thing to do is to have those stains done and await the results, instead of speculating on what it might be.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.