Cancer Community
I hope someone can help me understand this...
About This Community:

This patient support community is for discussions relating to cancer, cancer staging, chemotherapy, hormonal therapy, radiation therapy, surgery, and tumor types.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

I hope someone can help me understand this...

I recently had 3 moles removed from my back and sent to a pathologist.  My regular Dr. called and suggest that I set an appointment with a skin center (that specializes in skin cancer) immediately.  I asked my Dr. for as much info. about my condition, but never received a straight answer.  So, I then asked her for a copy of the pathology report, hoping that I'd be able to make some sense of this. Unfortunately, it just leave me more confused.  Here what it said:

Moles 1 & 2 - Melanocytes are present along the junction and within the dermis.  An aberrant architecture is observed with both stromal fibroplasia  and a lymphocytic host response.  There is atypia of the melanocytic cells characterized as marked with nuclear variability and hyperchromasia.  Though a nested pattern is present, a few single cells are also seen.  With the marked cytological atypia, this is classified as a dysplastic nevus with sever melanocytic atypia.  This is a high-grade dysplasia that borders on early evolving melanoma.  Atypical changes extend to the edges of the biopsy.  In view of the atypia, it would be prudent to ensure that the lesion is completely, but conservatively, excised.

Mole # 3 - There is a proliferation of atypical melanocytes arranged in solitary units and in nests at the dermal epidermal junction. The dermis contains infiltrates of lymphocytes and there are zones of fibroplasia.  Nests of benign appearing nevus cells are also present in the dermis.  The changes are not sufficiently developed to classify this lesion as melanoma in situ, but there is a high grade (moderately severe) atypia.  Atypical changes extend to the edge of the biopsy.  In view of the degree of atypia,it would be prudent to ensure that the lesion is completely, but conservatively, excised.

I have an apt. schedule in 3 weeks to have the moles "excised".  If anyone could help me understand the severity of this report, I'd be most thankful.

34yrs/White/Male.

Thanks,

Ryan
Related Discussions
Avatar_dr_m_tn
Hi.  "Atypia" is a term that doctors use to describe cells which are abnormal looking in appearance compared with the usual cells found in a given type of tissue.  In your case, they found the melanocytes (the pigment-containing cells of the skin) to have that abnormal appearance.  Atypia implies that the abnormal cells are not yet cancer, but have a high chance of developing into cancer later on.  That's why the pathologist is recommending that the moles be removed or excised.  "Conservative" excision means that the mole should be removed with a minimum of normal tissue included in the excision.

So basically, what you have is a pre-cancerous skin lesion or a very early form of skin cancer, which is quite treatable at this stage.
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Cancer Community Resources
RSS Expert Activity
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
Top Cancer Answerers
612551_tn?1247839157
Blank
Jerry_NJ
NJ