It seems that these medications are not very effective in pain relief in your friend. He may need some other medications. These medications causing more pain should be discussed with his doctor. Codeine and morphine are usually very effective in pain relief in cancer patients. In some cases parental drug therapy may be needed in the form of intramuscular or intravenous injections. Other therapies like yoga, relaxation exercises, meditation may provide stress relief and symptomatic relief. Do consult his doctor about most suitable pain relief medications for your friend. I hope it helps.
Best wishes and regards!
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