Cancer Community
sorafenib or sunitinib which one is better in mrcc?
About This Community:

This patient support community is for discussions relating to cancer, cancer staging, chemotherapy, hormonal therapy, radiation therapy, surgery, and tumor types.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

sorafenib or sunitinib which one is better in mrcc?

Hi my question is if the patient is diagnosed with mrcc then which targeted therapy is to be considered as a firstline treatment for mrcc? is it Sorafenib(Nexavar) or Sunitinib(Sutent)?
Secondly i want to know that if the patient is of mrcc with brain metastasis then shuld Sorafenib or Sunitinib be given or not? if yes then what could be the dose for these two drugs?
Related Discussions
Avatar_m_tn
Hi Mr amrish just saw your add, i think it is always better to given that very targeted therapy as first line who is having better the PFS and TTP , since sunitinib is having the PFS> 9 months than sorafenib or 6 months ,secondly i think it is better to give Interferon with avastin as first line as the PFS is far more better than sunitinib or sorafenib both.
Your second question of mrcc patient with brain mets , in the phase III data of sunitinib or sorafenib , in both the trials patient with brain mets were excluded from the trial.
Butt both sunitinib and sorafenib are having the ARCC'S data with brain mets.
I think both drugs can be given but it is always to see the other paramaters before starting the therapy like line of therapy, patient age, organ function, blood pressure, histopathology report etc.
thanks
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Cancer Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank
Top Cancer Answerers
1268057_tn?1431952537
Blank
Londres70
France