Taking Lipitor, Niacin and baby Aspirin 81mg to control cholesterol! Recently took a blood test and noticed elevated Creatine PhosphoKinase at 268! I exercise, diet and take medications mentioned as part of an overall plan to control cholesterol and blood pressure! Is this elevated CPK of 268 something to be concerned about! What is considered a dangerouis level of CPK? Is it possible CPK is a result of exercising(running and weightlifting) or is it the cholesterol medications that's elevating my CPK? Appreciate yours expertise and thoughts on this matter, Thanks!!
CPK is found in skeletal muscle and myocardium (heart muscle). Lipitor can cause various levels of elevation and associated symptoms like muscle aches, weakness and atrophy. The elevated CPK may be of no consequence or it may cause serious problems depending upon the degree of elevation and the symptoms. A severely elevated CPK can cause liver damage. I would consult with your physician to determine if this is a new finding. You should compare the cpk value to previous levels and also have your renal (kidney) function assessed. The cpk may be a result of your exercise activities but better safe than sorry. Good Luck
I have attached a paragraph from the package insert
Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria
have been reported with atorvastatin and with other drugs in this class.
Uncomplicated myalgia has been reported in atorvastatin-treated patients (see ADVERSE
Myopathy, defined as muscle aches or muscle weakness in conjunction
with increases in creatine phosphokinase (CPK) values >10 times ULN, should be
considered in any patient with diffuse myalgias, muscle tenderness or weakness, and/or
marked elevation of CPK. Patients should be advised to report promptly unexplained
muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Atorvastatin therapy should be discontinued if markedly elevated CPK levels occur or
myopathy is diagnosed or suspected.
You can read about the connection of statin (Lipitor) medicines on muscle function and myositis at www.tma.org. I would be concerned if your CPK (CK) level had increased since taking Lipitor. Do some research and speak with your doctor if you have concerns.
Copyright 1994-2017MedHelp International.All rights reserved. MedHelp is a division of Aptus Health.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.