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Help with interpreting genetic test result
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Help with interpreting genetic test result

Could someone please help me interpret my recent genetic test results.  Does this mean I have inherited the susceptibility from both parents? Is the reference to a one in ten risk considred high?

                          HLA TYPING REPORT

  CLASS I SEROLOGY HLA           HLA           HLA           HLA
                    A             C             B            Bw
-----------------------------------------------------------------
Demonstrated:
Probably Present:
Possibly Present:
-----------------------------------------------------------------

  DRB BY DNA       HLA           HLA           HLA           HLA
                   DRB1          DRB3          DRB4          DRB5
-----------------------------------------------------------------
Demonstrated:
Probably Present:
Possibly Present:
-----------------------------------------------------------------

  DQB / DPB BY DNA HLA           HLA          HLA
                                DQB1          DQA1         DPB1
-----------------------------------------------------------------
Demonstrated:     02MZ,0302     0301,0501
Probably Present:
Possibly Present:
-----------------------------------------------------------------
Excluded:


LEGEND
MZ = 01/03/05

COMMENTS:
9482289    HLA TYPING FOR COELIAC DISEASE
          INTERPRETATION:
          Alleles associated with coeliac disease are PRESENT.
          CONCLUSION:
          The presence of DQ2 (DQB1*02) or DQ8 (DQB1*0302) or
          DQA1*05 is consistent with the diagnosis of coeliac
          disease but the positive predictive value is low as one
          or other of these alleles is present in 60% of the
          population.

HLA typing performed by serology using T & B cells separated from
whole blood (unless otherwise stated) or DNA-based methods using
DNA extracted from whole blood (unless otherwise stated).  All
DNA-based results, with the exception of DQB1 and DQA1 typing for
coeliac disease and narcolepsy, are obtained by DNA sequencing.
(Reference DNA Sequences: IMGT/HLA Sequence Database V2.25,
17/04/2009). DQB1 and DQA1 typing for coeliac and narcolepsy are
performed with One Lambda Luminex bead technology.

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