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You can try OTC hydrocortisone cream. A long time ago my doctor prescribed that for me for hemorhoids, which might have been minor anal fissures. This was before it was common to find 1% strength of hydrocortisone cream OTC. Be sure to only use the least amount necessary to use and to follow directions. Do not use long term, since this is still a steroid cream. Used correctly it is safe enough or it wouldn't be allowed to be OTC, but just because something is available OTC doesn't mean that there aren't risks associated with it. Overuse of any of the steroid creams can thin out the skin. You don't want this to happen. Temporary use will help relieve the symptoms and can help.