p.v.l

i have a 30months old daughter ,she has developmental delay,latest mri suggest periventricular leucomalasia(show paucity of periventriventricular white matter more pronounced in the peritrigonal region on either side.myelination appropriate.venricals are normal sized.wavy margin of body of lateral ventricals noted.) preveous mri ,when she was 8months old suggested(there is mild thinning of the posterior body and splenium of the corpus callosum.this most likely represents posterior white matter volume loss.) ,i am confused in both reports, as i think that regions of white matter loss in both reports are different.secondly i want to know can p.v.l child lead to a normal life .thirdly i want to know whether p.v.l is a type of c.p or mongol.her karyotype is normal(46,xx).forthly ,is there any therepy or medicine,for such cases.

[isthiscp]

hi there my son is almost 3 and we have had major difficulties with these blooming MRI's!!! HIS first mri stated widening of the sylvian fissures, widening of the subarachnoid space, prominent peri-cerebral fluid spaces and white matter of high signal????? His last one done a year ago said that he has increased T2 abnormalities in the deep periventricular white matter posteriorly on both sides and that the brain is not myelinated??? He is pretty delayed globally, was(and still is to some degree) hypotonic. Right sided weakness, drop falls, limp, cant do stairs, has six-ish words. Doctors say he is perfectly normal!!!!!!!! What do you do?

[itsmethere]

I am a 25 year old young girl and have cerebral palsy and my MRI shows bilateral posterior periventricular leukomalacia.  I have a learning disability which does present some limitations but I can lead a relatively normal life.  I was a preemie, 33 weeks gestation, with a difficult  pregnancy and birth.  Were your children preemies as  PVL is found primarily in preemies?

There is no cure for the actual brain damage, but there is treatment for its physical effects.  Surgery, botox and exercise can all help the spasticity somewhat.  As for whether there is any genetic predisposition to CP, there is no definitive answer.  It is now thought that some fetuses, for genetic reasons, when subjected to infection and hypoxia would develop brain damage while others wouldn't.