Chemotherapy Expert Forum
Chemo for invasive ductal triple neg Ki-67 at 87%
About This Forum:

Welcome to the International Chemotherapy forum. Questions related to lung cancer will be answered by a medical doctor.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Blank Blank

Chemo for invasive ductal triple neg Ki-67 at 87%

Which chemotherapy drugs are advised for the above-mentioned breast cancer?
Tags: 87% Ki-67
Related Discussions
322973_tn?1239908038
Hi,
Chemotherapy regimens in breast cancer are usually decided based on several criteria. These include the stage of the disease, age of patient, tumor characteristics, hormone receptor status, Her2Neu status, cardiac condition of the patient, metastases present or not, prior exposure to certain drugs, newer markers (gene signatures, topo II expression), neuropathy, allergy, renal condition, etc.
Your question as to which drugs would work best for invasive ductal cancer, ER negative, PR negative, Her2Neu negative and 87% Ki 67 expression cannot be answered without knowing certain characteristics like age of patient, stage of tumor, setting of chemotherapy (neoadjuvant, adjuvant, metastatic) etc.
In general, studies over the last three decades have proven that anthracycline (doxorubicin, epirubicin) containing regimens are superior to non-anthracycline regimens. Also, taxanes (docetaxel, paclitaxel) add clinical benefit to patients with high risk breast cancer.
Triple negative cancers tend to be more aggressive in nature, so in the adjuvant setting, many oncologists would prefer to use a three drug combination that includes a taxane, an anthracycline, and cyclophosphomide.
All the best, and God Bless!
Blank
Continue discussion Blank
MedHelp Health Answers
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
RSS Expert Activity
233488_tn?1310696703
Blank
Marathon Running Done Over Many Yea...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
233488_tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
May 21 by John C Hagan III, MD, FACS, FAAOBlank
748543_tn?1371753642
Blank
TMJ/TMJ The Connection Between Teet...
Jan 27 by Hamidreza Nassery , DMD, FICOI, FAGDBlank