My mother has stage 4 OvCa, DX May 2005 and is now into her 4th year. She has recenly finished a combination of Avastin,Gemzar & Carboplatin (carboplatin on alternate weeks). and her CA125 is 8. Is there anything else to try after Avastin?, I get the impression that Avastin is the end of the line for this rotten disease. A few years ago she was taken off Carboplatin and Taxol due to it giving her tinnitus so what else can she try, would Avastin still work if it was combined with something else ? Over the years she has had Taxol & Carboplatin then onto Doxil & Gemzar together. I know time is running out for my dear mum but we are always hopeful of something else. Thankyou for your time.
There are many approved chemotherapy options still left. She appears to be platinum sensitive, as carboplatin is still being used.
According to the standard NCCN (National Comprehensive Cancer Network, nccn.org) guidelines, recurrent ovarian cancer may be treated with two drugs (one of which is a platinum), or a single agent like docetaxel, oral etoposide, weekly paclitaxel, pemetrexed, topotecan, cyclophosphamide, capecitabine, irinotecan, vinorelbine, hormonal therapy, local radiation, etc.
Avastin is certainly not the end of the road. Ovarian cancer is relatively chemosensitive, and many women with recurrent disease do well for long periods of time.
All the best, and God Bless!
Copyright 1994-2017MedHelp International.All rights reserved. MedHelp is a division of Aptus Health.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.