Treatment in ovarian cancer: hilar and mediastinal lymphadenopathy
In treating ovarian cancer that is now apppearing in these lymph nodes as well as a pretracheal node...would you continue your current treatment (Hexalen) ...only one round so far trying to get CA125 stable-and obviously not working ..or change to a more aggressive treatament such as Avastin+?
I am not sure I fully understand your question.
Altretamine (Hexalen) is used after failure of at least a couple of lines of therapy, so in this case, the ovary cancer has obviously failed to be controlled by more effective therapy like carboplatin and paclitaxel.
A stable CA 125 is an indirect measure of chemotherapy efficacy, although a PET-CT showing regression of nodes is much preferrable.
Avastin controls cancer by chocking off the blood supply feeding the cancer cells. It is usually more effective if added to a chemotherapy drug rather than being given as a single agent.
Pl post additional questions if you need clarification.
All the best, and God Bless!
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.