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carboplatin without paclitxel?
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Answered by Kamal S Saini, MD, MRCP (UK), DMBlank

carboplatin without paclitxel?

My partner has been diagnosed with stage 1c ovarian cancer and must undergo chemo. After debulking all biopsies and peretonial wash show no cancer cells. In your opinion woiuld treatment with carboplatin only be reasonable in this situation?
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Hi,
I know of practicing GYN oncologists who would be perfectly comfortable giving their patients with low grade Stage IC ovary ca chemotherapy with single agent carboplatin.
However, standard 2009 guidelines (National Comprehensive Cancer Network, www.nccn.org) are unambiguous in their recommendation that all Stage IC epithelial ovarian cancers of any grade should receive combination of a taxane and carboplatin for 3 to 6 cycles.
If your partner is in good health, I personally would prefer a carbo-pacli combination regime for 6 cycles.
All the best, and God Bless!
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