My mom (69 years old) was diagnosed with ovairan cancer 3 years ago. Her ovaries were removed and she went through 6 weeks of chemo with taxol and carboplatin. Her cancer is back and her Dr. wants to use the same chemotherapy regimen for her. Isn't there newer more effective treatments available now? Is there anything we can do to prevent her cancer from coming back or lengthen her remission period?
The most effective and commonly used chemotherapy regimen for ovarian cancer as of today still remains the combination of paclitaxel (Taxol) and carboplatin (Paraplatin).
In cases where ovary cancer relapses, we measure the time since stopping carboplatin based chemotherapy and the reappearance of ovarian cancer. This time period is called the "platinum free interval" in oncology parlance. If it is over 6 months, the tumor is potentially platinum sensitive, and if over 12 months, it is even more likely to be platinum sensitive. This means that the recurrent ovarian cancer is quite likely to respond if carboplatin based chemotherapy is repeated.
Hence the oncologists' decision to repeat carboplatin-paclitaxel in your mothers case is sound, as she has had over two and a half year of platinum free interval.
There are many other effective drugs for ovarian cancer including cisplatin, docetaxel, gemcitabine, liposomal doxorubicin, etoposide, pmetrexed, topotecan, cyclophosphamide etc. Targeted drugs like the anti-VEGF antibody bevacizumab (Avastin) is also being tried in this setting.
She is likely to respond and go into another remission, during which she must be under active surveillance with periodic imaging (CT or PET-CT) for early detection of any relapse.
All the best and God bless!!
Copyright 1994-2016 MedHelp International. All rights reserved.
MedHelp is a division of Aptus Health.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.