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Kevin Kennedy, Ph.D. - Child and Adolescent Psychotherapy, Family Therapy, Crisis Intervention
Harvard Vanguard Medical Associates
This forum is for questions and support regarding child behavior issues such: Child Discipline (behavior management), Normal Child Development, Parent-Child Communications, Social Development
Diphenhydramine hydrochloride is an anxiolytic and tends to sedate children, and it is not unusual to see it employed as a short-term remedy. However, it is not a good idea to use it for a protracted period of time.
I wouldn't try it all. I gave it to my daughter for an itch and it sent her over the roof. And it warns on the bottle that it may cause excitability in small children. The warning is mild.
I am assuming you are doing the usual things like quiet activities before bed, lite snack with protein, story time, and bed time limits.