I am with Sally44 on this one. Autism-like and sensory symptoms in young age also signalize a mood disorder which cannot be diagnozed until older age....Bi-polar, depression, etc....Since sounds like your wife has it (she was taking anti-depressants), or at least prone to it, I would consider it as well....By the way, they are finding more and more liks between mood disorders in parents (esp. bi-polar) and autistic traits in children.
Goo luck with everything
He he been assessed by anyone yet? I think it would be useful for a Speech and Language Therapist to assess his speech and social interaction skills. They should assess his expressive and receptive skills as well as auditory memory and working memory skills. Because of the issues with eating/not eating/biting etc I think it would be useful for him to be seen by an Occupational therapist. Google Sensory Integration Disorder to see if that sounds relevant. With SID the senses can be over or under active or can fluctuate between the two day by day and throughout the day. So the sensation of being kissed may feel unpleasant or even hurt him and he might react by biting. If his senses become under active then children start to show sensory seeking behaviours such as mouthing or chewing things, making lots of noise, seeking all kinds of movement etc. If the sense is hyper active they tend to show avoidance behaviours eg. avoiding touch, avoiding eating/drinking, covering ears at noise or appearing deaf when spoken to. The sense of proprioception tells the body parts where they are (ie. how to move your body in space). So problems with co-ordination or with understanding internal sensations such as hunger/thirst/needing the toilet/feeling hot or cold are all controlled by the proprioceptive sense.
You say he needs to be told repeatedly to do something, and even then may not do it. Does he appear not to hear you, or does he hear but not know what to do? If he appears deaf it could be down to SID, if he appears not to understand you need the speech therapist to assess this. Also google Executive Function Disorder to see if that sounds relevant.
Your child maybe on the autistic spectrum. I am not a professional, just a parent of a child on the spectrum. I think it would be sensible to ask for him to be referred to a multi disciplinary team (ie. SALT, OT, Paediatrician, Clinical Psychologist etc), for them to assess him and for these professionals to be experienced in diagnosing autistic spectrum disorders.