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Dear Nancy,
As you probably already know, one of several distinguishing features of Pervasive Developmental Disorder is an impaired ability to interact with others, to maintain reciprocal social interactions. Because of their idiocyncracies or peculiarities, children with PDD are often shunned by their peers - they are seen as "different", and peers often do not readily relate to them. At the same time, many children who display PDD are not unaware of the reaction of others - they feel left out. This can be quite disheartening and lead them to develop negative self-perceptions.
Stress is frequently a contributing factor, and sometimes even the main cause, of headaches. Persistent, recurrent headaches certainly warrant evaluation. If the pattern to the headaches indicates that they are associated with unsatisfactory interactions with peers, the headaches may well be due to the stressful nature of your son's peer relationships.
Children with PDD, depending on the severity of the condition (and there is a wide range of variation), improvements in relational ability can be achieved, but such improvements do not, generally, occur spontaneously. They occur when children participate in therapeutic groups, which have as their goal enhancement of social skills/social problem-solving skills. The more cognizant the child is about the nature of the peer-related difficulties, the more optimistic the prognosis for improvement.
As a parent, you are absolutely correct to engage in sensitive listening when your son speaks with you about his worries. You can't be his therapist, but you can try to locate help for him, such as the type of group therapy I mentioned above.
Relative to possible depression, it is not a condition which is necessarily associated with PDD, but children who display PDD may well display a depressive disorder as well. It would be wise to have your son evaluated by a child mental health clinician - part of the evaluation could also address his PDD-related needs, and the clinician could be helpful in locating a social skills or social problem-solving group.
This information is provided for general medical education purposes only. Please consult your physician for diagnostic and treatment options pertaining to your specific medical condition.
*Keyword: Pervasive Developmental Disorder