Aa
A
A
Close
Avatar universal
What if Azithromycin & Doxycycline Don't Work?
About 6 weeks ago, I picked up chlamydia from my girlfriend.  As this is my first (and hopefully last) experience with an STD, I'm a bit of a novice as far as treatment is concerned.  3 weeks ago I went to see my primary care doctor (about a week after symptoms began) complaining of a slight itchy/burning sensation during urination.  I did not have any discharge at all.  I was tested and came back positive for chlamydia.  Here is what transired after this:

- 1 day before test results, doctor prescribed 400 mg of Suprax
- The day the test results confirmed I had chlamydia and not gonorrhea, I was given 1500 mg of azithromycin.  I took 1 gram the first day, and 500 mg the 2nd day.
- 5 days later I still had symptoms, so I saw a urologist.  He ran another test (which subsequently came back positive for chlamydia), and prescribed 100 mg of Doxycycline twice per day, for 14 days.  

I am now on day 12 of the Doxy, and I still have symptoms.  My last pill will be Tuesday morning, and I'm scheduled for another test on Thursday.  And now for the questions:

Is it likely at this point that the Doxycycline has not worked?  If so, is it worth asking for a different antibiotic rather than wait 5-7 days for test results to come back and not be on meds during this time?  If so, what medication is most appropriate assuming azithromycin and doxycycline did not work?

Thanks in advance.
Cancel
17 Answers
Page 1 of 1
Avatar universal
Chalmydia symptoms can sometimes take a while to resolve themselves and anti-biotics are a slow release medication, meaning they are still working to kill an infection for some time after you've swallowed your last pill.

I had what I assumed was a drug-resistent case of chlamydia (which is essentially unheard of, from what I've been reading) because my symptoms persisted after a few different treatments.  I was diagnosed on 7/16 and was prescribed 7 days worth of doxicyclene but on the sixth day it didn't seem to be working so my doc switched me to 1 gm azithromycin and 1 gm metrodinazole.  A week after the azithro/metro treatment, I was still having that post-pee sting.  My doc put me on z-pack.  On the last day of z-pack (8/6) , I went in for another round of STD testing and the test from that day came back as negative for chlamydia.  I was still having a some slight urethral discomfort three or four days after completing the z-pack (maybe up until 8/9 or 8/10), even though the chlamydia was gone.

Give it time to work, but keep on your doctor if your issues persist or if further tests come back positive.  There are other anti-biotics they can give you.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Thanks for the feedback.  I suppose I'll wait to see the outcome of this test, although the symptoms really don't seem to be improving much... they were slight from the beginning.  

Has anyone had experience with either Cipro, Levaquin, and erythromycin?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
736575 tn?1288906158
You are testing too soon.  You really should not test any less than 30 days after the first day of treatment.  The tests are picking up dead chlamydia dna.  Give it time and go for a test for cure in 30 days.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Interesting... Most of what I've read and heard (including from my doc) was that the risk of being tested too soon was a false negative, since the presence of antibiotics can mask the bacteria.  Tomorrow is the re-test, and will be about 23 days since beginning treatment.  Fingers crossed.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
I am having the same problem you seem to have had, i underwent about 6 months of different treatments and tests before i finally switched Docs, and right away she found out my husband had given me chlamydia. I took 2 days work of azith/metro and then started a 14 day cycle of doxy, 100 mg 2 times a day. I am having NO relief of the "post pee sting" i still feel like i have to go ALL the time, loosing sleep over it every night im 12 days into doxy and i have had no help, im going in 3 days for a pelvic ultra sound and a request for more antibiotics, I am afraid that nothing is going to work its been 7 month since ive had this problem and even with the medication the problems seem worse. what should i do?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Keep working with your Dr's on this issue. Have more urine/swab testing. Get off medication for about 2 weeks and see what happens.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Hi everyone. I'm suffering with the same ********. 4-5 months in. The meds seem to be making my pain worse. What the hell am I doing wrong? No matter what I do its not getting any better. It started with my dick burning when I pee. Then after I per when the clap travelled to my bladder. Then I turned into Epididymitis. Now it's getting in my ******* eye. I feel like ducking dying. Someone please help. This whole time I've been going back and forth between doctors. I've tried everything. Please for the love of God help me.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Start your own thread please
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
I don't want to scare anybody, but probably I will. I was diagnosed with chlamydia more than a year ago and I had 7 or 8 (I forgot the number) unsuccesful therapies with antibiotics (each between 20 and 30 days and by the book).

I'm currently on multi-antibiotic therapy for a month. I'm getting used to the idea that my life is ruined and I think that there is multi-antibiotic resistant chlamydia out there, but it is still not on the news.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Hello. Just to say that I'm finally cured! Don't give up!
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
What is the medication that cure clamidia? Thanks!
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Start a thread for your question and we do not give medication info out. See your Dr.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
What finally helped cure you?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
InfectedForLife: what did eventually help you? I am in the same position, got chlamydia almost a year back, tested about 2-3 months later (quite late I know, wasn't paying attention to the sympthoms enough), over time went through weeks of doxycycline, azithromycin in higher doses than usual...always just temporary help from sympthoms. Now I can feel it coming back and just waiting these useless 3-5 weeks to get retested. Not to mention that my GP just keeps telling me that it is unheard of that these treatments fail, probably secretly thinking I'm lying.

Very happy to hear though that there is still some solution!
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
I have Chlamydia from long time before i dont know what is this and not feeling anything just some drops come after urine. before i thing its normal but when i search about that really its a big problem. from 5,6 month i was felling burning in my eyes and feeling tiered every time even if i sleep 20 hours. After that i take doxicyclene for a week after that nothing feel better. Then i found natural treatment for Chlamydia by garlic. I eat 3 piece of garlic in a day after one week i feeling better. now i am ok no eyes burning and no feeling tiered but some drops still coming after urine.

If you can eat garlic its better for your eyes and body pain. Must be eat chop garlic 3 or 4 piece in a day with empty stomach.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
When were you exactly cured ?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
I believed there's no medication to kill the chlamydial upto 2016.
1. It's not the bacteria. It's virus.
2. There's no commerical value to invent the remedy.
3. There's a vaccine to protect the people - avoid the infection. However, they recently found it improperly apply to user. They are correcting it and release soon. But, vaccine is used for the persons who hadn't have chlamydial - not us.

eradicate
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Your Answer
Avatar universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
Submit Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Chlamydia Community Resources
RSS Expert Activity
233488 tn?1310696703
Blank
Marathon Running Done Over Many Yea...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
233488 tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
748543 tn?1463449675
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank
Top STDs Answerers
Avatar universal
Blank
Avatar universal
Blank
Gent, Belgium