Chronic Fatigue Syndrome Community
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Chronic fatigue syndrome (CFS) is a disorder that causes extreme fatigue over extended periods of time which persists after rest and limits one’s ability to conduct ordinary daily activities. Discuss topics including causes, exams and tests for CFS, treatments and how to live with CFS.

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Hi,

Could anyone tell me if CFS is related to Ehlers-Danlos syndrome.

Thankyou
Avatar_dr_f_tn
Hi,
As mentioned from the other post, Ehlers-Danlos syndrome is a group of inherited disorders and there has been some  studies that show EDS in patients with CFS and orthostatic intolerance.  The occurrence of these syndromes together  is said to be attributed to the abnormal connective tissue in dependent blood vessels of those with EDS, which permits veins to distend excessively in response to ordinary hydrostatic pressures- which in turn leads to increased venous pooling and  the symptoms. However, additional studies may need to be done also. It is best that you discuss this also with your doctor for proper evaluation.  (ref: http://www.ncbi.nlm.nih.gov/pubmed/10518084 and http://www.ednf.org/index.php?option=com_content&task=view&id=1245&Itemid=88888988).  
Take care and regards
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