Hi. The use of immunosuppressants is very unusual. They should only be considered when dogs are already being given standard therapy and the serum creatinine is greater than 3.0 mg/dL, azotemia is progressive, or hypoalbuminemia is severe.
The question is, has this protocol been followed by your vet? I would certainly be asking the question, because there are many other far more likely successful protocols with chronic kidney disease other than the use of immunosuppressants. One of the big problems of the latter is they increase substantially the toxic load (due to by-product metabolization of the drug), which in turn stresses the kidneys far more.
It would help enormously if you could post blood and urinalysis results - and confirm that your vet has undertaken a blood pressure check. Also, has the vet suggested necessary diet changes?
Regards
Tony