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Is this PFT showing Asthma or COPD?
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Is this PFT showing Asthma or COPD?

by win904, May 12, 2009 02:15PM
I have severe allergic Asthma and have been in the hospital and urgent care numerous times this year, I've been on massive steriods this year.  I'm taking Q-var, Symbicort and Zyflo along with Allergra.  My peak flow goes up and down at the drop of a hat. I'm on Xoliar and weekly allergy shots too!  I have a continual cough that will wake me up at night and I cough during the day from time to time.
My Pulmonary function test results were as follows:
FVC 55% Post 7%, FEV1 L 61% Post 2%, FEV1/FVC%112%, FEF25-75 87%, post -20% FEFmax 95% post 6%
Lung Volumes:
VC 61%, IC 77%, ERV 26%, FRC 54%, RV 69%, TLC 64%, RV/TLC 108%
Diffusion Capacity
D/VASB 178%, DSB 114%, VAsb 64%
This report showed Moderate restrictive ventilatory impairment with no significant improvement post bronchodilator. Can this be the cause of my servere asthma? No sign of upper airway restriction on the report.  My dad had interstitial lung disease, COPD and emphysema.  My cat scan showed small nodules in my lungs. Re check in 6 months
Can anyone tell me what is up?  I'm heading out to the National Jewish in June, thanks!

by National Jewish Health, May 21, 2009 05:07PM
You have made a good decision to come to National Jewish Health®.  I am a physician on the staff at National Jewish Health®.  You will be seeing one of my colleagues and I can assure you that you will receive good care.  Your pulmonary function tests (PFTs) show mostly features of restrictive and, given the degree of restriction, fairly normal flow rates, without a bronchodilator effect.  Restrictive features include the reduced total lung capacity (TLC), vital capacity (VC), and residual volume (RV).  The nodularity noted on your CT scan would be quite atypical for asthma and a much more common feature of a variety of restrictive lung diseases, including interstitial lung disease.

You may have asthma but that is not reflected in your PFTs.  A rare form of asthma, with restrictive features was described by Hudgel, Cooper and Souhrada in the Annals of Internal Medicine in Sept 1976, Reversible Restrictive Lung Disease Stimulating Asthma but that must be extremely rare and the odds, in your situation, would highly favor restrictive lung disease.  You may need a lung biopsy to establish the correct diagnosis.  Also to be considered is a condition called vocal cord dysfunction (VCD).  This condition can mimic asthma and could be superimposed on asthma or restrictive lung disease.

Good luck.

Please, let us know what the National Jewish Health® doctors conclude and recommend for your lung problem.
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