Colitis Expert Forum
recurrent C diff want gone, not treated
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recurrent C diff want gone, not treated

Im 25 and was found to have C diff after  a week stay in the hospital for acute infectious colitis. I was on IV Vacomycin until i left with a script for flagyl 250mg every 8 hours for 10 days. also They gave me a diet of no gluten that i dismissed because bloodwork did not show celiac disease. within a week after finishing the flagyl, I had gotten a fever and swollen right lower side for about 2 days. I was given Cipro for something else. the pain and diarreah (diarrhea) returned and i knew this was c diff having just been through this weeks before. At this point my health care has expired and I didnt have 50 bucks to go to my pcp. My doctor was nice enough to phone in the same 250mg. flagyl and had also put a refill on it. I started feeling better within 4 days. Im currently on the refill and am terrified that when I have none left this disgusting infection will return, AGAIN. Im finding more and more that C diff tends to reoccur after meds or being on other antibiotics. So Can you actually get rid of C diff or does it linger in youre bowels forever, waiting to erupt?
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Hi,
Despite initial treatment success, 15% to 20% of patients have recurrence of diarrhea in association with a positive stool test for C. difficile toxin. Recurrent symptoms appear most often within one to two weeks of discontinuing therapy, but can appear as late as one to two months.

It results from germination of C. difficile spores persisting in the colon despite treatment.
The treatment of a first relapse does not differ from treatment of the initial episode.  Diagnosis should be confirmed prior to reinstituting therapy. Patients with mild symptoms can be managed without antibiotic therapy, but if symptoms persist or are severe, a second 10- to 14-day course of metronidazole or vancomycin can be started. Most patients will respond again to the same specific therapy,and 90% will not experience further recurrences.

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The information provided is for patients’ education only and is not a medical advice. Always consult your personal physician for complete evaluation of your health problem.

- Ratnakar Kini M.D.
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A related discussion, Recurrent C. diff Treament from Mayo Clinic was started.
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