Furosemide questions

What is the difference between furosemide prepared for IV bolus v.s. furosemide prepared for IV infusion? Can you mix furosemide prepared for IV bolus in saline and use it for infusion, or does this reduce its effectiveness?

[Dr_Veena]

Hi,
     Any drug given for fast input function is called as bolus and does contain higher concentration of the drug. While infusion is a giving a drug intravenously slowly over a period of time, as required. Furesemide bolus is given over 1-2 minutes with dose upto 100mg. Infusion is given with doses upto1- 10mg/ml and is compatible with D5W, NS, LR, D5S solutions. You can use furesemide bolus for infusion by mixing it with compatible solutions, but it’s effectiveness is not reduced, as infusion is given to maintain the concentration of the drug constantly in the body. Best.