Is there anything we can do to speed up the process to get to a diagnosis?
My wife has had chronic diarrhea, malabsorption, and weight loss for over 4 months. She continues to lose weight, from 140 to new low 113.2 today. The GI at Wake has her on a 2 week gluten-free diet. We are 3-days into the diet with no change. We know that a test showed low pancreatic enzymes and a biopsy severe colitis in her lower colon (GI said it looks like colitis caused by acute infection, but no infection found). Many tests (stool/blood) and biopsies have been done, all negative.
Symptoms: Eczema(spots don't go away), hair loss(minor), hidradenitis suppurativa, numerous infections, enlarged spleen (removed), chronic diarrhea/constipation (10+ years), and now severe diarrhea w/ malabsorption
Current treatment: 1-2L IV, Lialda (4/day), prednisone 40 mg/day, enzymes MT-10 (2/meal), pot KLOR-20 (4/day), gluten-free diet for 2 weeks. GI surprised enzymes not helping, but does not put as much stock in the enzyme test as his collegues.
1997: diagnosed Ulcerative Colitis (mild)
2004: C-section, several months after cellulitis with abscess
2005: severe pneumonia, w/ sepsis (Xigris), pulmonary abscess from pneumonia (Primaxin), enlarged spleen
2006: enlarged spleen removed laparoscopically
2008: C-Section, cellulits
Feb: chronic diarrhea started, watery, a bit oily, chunks of food, frothy at times
Mar: Colonoscopy - microscopic colitis, hospital c-diff (only one test had weak positive) (flagyl, 2 courses vancomycin), no change, then prednisone 10mg/day 5 days, 5 mg 7 days, diarrhea slowed a little while on steroid
May: hospital dehydration, low potassium (2.3), referred to Wake Forest GI
Jun: Hospital pneumonia, UTI, low pot(3.2) (vancomycin/doxycycline) (IV home, potassium)
- MRI at Wake (suspected IBD) neg. (Lialda 1.2 mg (2/day), continue other meds)
- Wake Colonoscopy/EGD – biopsy severe colitis colon, not ulcerative, not c-diff, no celiac.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.