High doses of prednisone can caused chest pain.
I was diagnosed with Crohn's 3 years ago. So, I can only tell you from personal experience since I'm not a doctor. Chest pain could be heartburn because Crohn's can affect any part of your GI tract...it could be ulcerations also...have you had a gastroscopy? Other reasons: anxiety...either from the disease or medications you might be taking, or GB problems...which can be associated with Crohn's. My suggestion...watch your diet and see your doctor.
I get that too. I think it's heartburn?