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Prevacid is used mainly to protect the stomach from ulcers etc. You probably should be talking to your sons doctor or pharmacist and ask if it is ok that he takes the prevacid when he has an allergy to penicillin. A lot can also depend on the type of reaction he gets from the penicillin as well. So my advice would be just to call up your pharmacist or doctor and ask. It never hurts to be safe rather then sorry. Hope that helps!