Unfortunately there is as yet no treatment to stop the damage done by MELAS syndrome, and the outcome for individuals with the syndrome is usually poor. Moderate treadmill training can help improve the endurance of individuals with myopathy. Metabolic therapies, including dietary supplements, have shown benefits for some individuals. These treatments include coenzyme Q10, phylloquinone, menadione, ascorbate, riboflavin, nicotinamide, creatine monohydrate, idebenone, succinate, and dichloroacetate. Whether these supplements will help all individuals with MELAS syndrome is still being studied.
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