spasms in hands, muscle cramps due to neurological source?

I am a 51 year old female.   I have asthma, controlled now, and sleep with a CPAP machine.  For several years I've had severe spasms in my arms and hands.  They come on unexpectedly.  Sometimes I throw pens or forks.  Sometimes I simply can't hold such objects because of recurring spasms.  Sitting on my hands seems the only way to keep them from spasming.  Holding and using tweezers is often impossible.  The spasms sometimes extend into my forearms.  I also get horrible cramps in my legs at night sometimes.  These cramps center in my upper thigh and are acutely painful.  The only relief I get is to stand on the affected leg and try to walk it off.  If I stop walking too soon, as soon as I take my weight off the leg, the cramp returns. Recently, I've begun to experience a burning pain around the ankles at times.  (They sometimes swell). I was diagnosed with some rare condition of the vessels of my brain 2 years ago.  Apparently the walls of my vessels are unusually thick.  Some neuro hyperplasia.  Perhaps this extends to other vessels in my body?  Could all this be vascular? My spinal column is also only 80% the diameter of the average person's.  I also have some partial feeling in my fingers, but attributed it to the aftermath of cervical spine surgery.  The numbness in my leg and foot ARE the result of lumbar injury and surgery in 1993.  

[Enoch Choi, MD]

I'm sorry i'm not familiar with neuro hyperplasia.  Did the doctor describe this to you?  Is it an overgrowth of the nerve linings?

What does your neurologist say about the spasms?