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If you need extraction or other surgical interventions, consultation with your primaryPrimary amyloidosis Primary biliary cirrhosis Primary hyperparathyroidism Primary insomnia Primary lymphoma of the brain physician is advised. If you do'nt have Paget's disease or growth hormone problem, such as acromegaly , your jaw bone is relatively stable, there is no contraindication of removable partial denture. Even you have above medical conditions, fabrication of removable partial denture is still manageble.