It would depend on how severe is your saliva flow. It becomes very difficult to have any long lasting results with any treatment because the low flow of saliva makes food stick to everything and can cause cavities and gum disease. You may want to discuss with your MD and dentist about the medications and see if there may be alternative meds that can be used to help with the saliva problem. Even with a denture, it may be uncomfortable as food can get stuck underneath and won't wash out as easily. It is very important to address the dry mouth with home care, different types of toothpaste, mouthwash, etc. Be sure to try to chew more sugar free gum, carry a bottle of water, etc to keep the mouth moist.