Can 150mg of Zoloft be too much?

I was recently upped to 150mg of zoloft.  I had been on 30mg of lexapro for six weeks and seemed to be getting worse.  He had me switch to 100mg of zoloft for a week and then in a week increase to 150mg.  Since I'v been at 150mg, I have felt very tired and more anxious at the same time.  It has been causing me to take xanax again after almost stopping.  I was down to less than 0.5mg per day.  Now I'm back to 1.0 to 1.5mg per day for the anxiety.  Obviously, I don't like taking xanax because of the addiction potential.  Can you help?

[Roger Gould, M.D.]

150 mg by itself is not too much, depending on your size and weight, but it sounds like you have a paradoxical effect...more anxiety rather than less, and this sometimes happens for people because Zoloft has a stimulating effect.   Talk to your doctor about changing the medication....