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Can Midazolam - (known as Versed) have permanent side effects?

Can Midazolam - (Versed) have permanent side effects or do they wear off eventually?

Dosage: 11-12 mg of Midazolam over about a 10-12 minute time frame through IV line for a medical procedure. 2mg each 1-3 mintues until fully sleeping.

Problem: Difficulty analyzing things or understanding mostly on when I try to verbally explain something. Some things that should be normal now seem confusing, things that I have discussed with people easily before receiving Midazolam are difficult. It is affecting my ability to work/business.

Even after I understand the subject it is still difficult to understand it when think about it. The part that is difficult is when I need to come up with new creative options based on understanding subjects or when I need to come up with ideas and explain them to someone else verbally.

Example that happened the other day... A store is generating 3 times the business in almost the same location but new building, I was trying to analyze why. I was working on this before given this drug but now it's very confusing to me.

I also forgot recent things like my 4 year anniversary, new bank accounts, some things that was only 2 months before the procedure. Had no idea until I saw a bank statement or went through pictures of other anniversaries.

It's over a month already. First I thought the drug didn't wear off yet, then not enough sleep, then not eating enough. Now I'm wondering if it could be a side effect? My job is to analyze things because that used to come so naturally.

My chart said my oxygen levels were normal however blood pressure did drop near or more than -20 points both top and bottom numbers. I was mentally or physically to sleep for about 40 minutes.

Could the drug still be wearing off after 40 something days?

To complicate things I am also feeling pins and needles in the face-head which is mostly consistent but they could have twisted my neck hurting an old injury.

Could all this be from Midazolam?
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Avatar universal
It all sounds rather brutal and confusing.

It doesn't elicit trust when a health professional omits, or misrepresents, facts.

Talk to your neurologist about it, and if they don't know, ask if they can direct you to someone who does.

It also sounds like talking this through with someone might help.

Have you tried searching either your symptoms, or side-effects of the drug, or both?
Could it be a nerve problem?
I understand how important it can be to have answers, but don't do this at the expense of your health (unless there are benefits to be gained).

J
Helpful - 0
Avatar universal
The pins and needles seems to get worst and move around. It's definitely some kind of problem probably not related to the drugs if not perfectly constant, but it wasn't there before so it is definitely related to the procedure in some way. They were doing an endoscopy too, so they could have been forcing my neck in to a bad position. I was going to say something about my old neck injury but since no drugs were going to be used it didn't seem needed to discuss. Or it could have been my high pulse for that duration if there was a problem elsewhere. Either way it's definitely not anxiety.

One of the frustrating things after being drugged was problems blurting things out that normally I would just think about and not say. It's gotten better since a week after but I still blurt things out that I'd rather not have said here and there.

I don't even know if they gave me more of that drug, but that was what was documented so I have to go by my chart. After I was drugged I was forgetting to do things I needed to do, I just seemed not to notice that things needed to be done, or didn't care, but that wore off after about a week. Just not completely. I still can't remember my 4 yr anniversary and still have a very confused feeling about specific types of things that I try to think about. Yet other things are as easy as pie. Then I also know I need to understand that if the pins and needles are blood flow, well that says a lot there. But I can't see why I would have any problems like this from an endoscopy, colonoscopy? So it leads me to the drugs. Pins and needles could be a different issue. Don't know. Hoping someone familiar with the drug and side effects can help.

I have to make an app with a neuro doc for the pins and needles. Not good to have in the face. I have no memory of the after being drugged but I would imagine if I learned they were drugging me I probably would have put up a fight to get out, who know if they were holding me down to drug me further and twisted my neck?

The funny thing is that the doc told me after procedure he understood I said no drugs and denied ever drugging me. Said I did not get drugs. I had to pull hosp records to find out how I went out.

I just want to know how much of this can if possible be related to this drug and whether it is permanent or if eventually (how long) for my brain to return back to normal. I already understand if it is blood flow that's another story. My question if specifically related to this drug.
Helpful - 0
Avatar universal
Could it have had anything to do with the operation itself?  I.e., What the operation was for.

Pins and needles can also be related to anxiety and hyperventilating.

I can relate to some of the symptoms you write about.  I experienced mine after being forced to take 40 mg of prozac (which I stopped the day I was discharged from hospital).
I can't say for sure whether it's the medication, the anxiety, changes in brain structure/ physiology, etc.  I'm not even sure it wasn't the contrast used for a CT of my head.

I do have some good head days though, so I think it is more likely to be either diet or stress related (I have periods of extreme binging and extreme restricting and my stress levels are generally pretty high).

Maybe you're dissociating??
Maybe you haven't come to terms with the medical procedure??

I wouldn't have thought a 20 point decrease would have been too concerning (not if you're generally fit and healthy).

I had minor surgery recently and my resting heart rate was 59 bpm also.  (It was 42 before surgery that morning).
My HR remained elevated for several weeks post surgery (it may have been longer, I didn't record the figures).  I think it takes a while for our bodies to recover.

I took massive quantities of prozac and other stuff (discharge meds, etc).  Please note: this is most definitely not advised.  Anyway, my HR went up to 91 then down to 36.  (It was 248 + during an asthma attack).  My BP was 79/ 24.
I think it takes the body a while to recover and to restore homeostasis.

It seems a bit strange that yours remained elevated.

My feeling it that it is more stress related than anything else.  (I can't go wrong by saying it's stress either because I believe most, if not all, disease processes begin with stress of one sort or other).  OK, so that wasn't very helpful.

I'm allergic to midaz so I was intrigued by your post.

I hope you're able to find some answers (and resolution of your symptoms).

J)
Helpful - 0
242532 tn?1269550379
MEDICAL PROFESSIONAL
I am not qualified to give you the answer you are seeking . The right person would be an anesthesiologist who has worked with this medication...you can be assured that there is no medication  left in your body, and unless there is some particular   rare side effect like you are describing, it is extremely unlikely that the symptoms you desribe are related to the medication.
Helpful - 0
Avatar universal
I don't know if this is relative. My pulse before Midazolam was 59 bpm resting. After Midazolam it remained around 90 bpm resting (laying down) and pressure was lower than normal.

It took about 20 days for my pulse to drop and pressure to come back up. I thought the high pulse was causing the pins and needles but my pulse/pressure returned to near normal and pins and needles face/head, ect.. are still here.
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