Depression/Mental Health Expert Forum
Clozapine effectiveness in the presence of other meds
About This Forum:

This forum is for questions and support pertaining to mental health issues such as: Anger, Dementia, Depression, Family Problems, Memory Problems, Personality Disorders, Phobias, Schizophrenia, Transitions and Work Problems.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Avatar universal
Clozapine effectiveness in the presence of other meds
My wife has been on Trilafon and recently added Clozaril for her Schizphrenia. She is still having problems. Her Dr. says that other anti-psychotics can interfere with clozaril's effectiveness. Is this true, has any evidence been found to support this?

Thankx,
Dwight
Discussion is closed
Cancel
2 Answers
Page 1 of 1
Avatar universal
The information packet of Clozaril indicates that the risks of  using Clozaril in combination with other drugs have not been systematically evaluated.

However, the concomitant use of Clozaril with other drugs (like Trilafon)metabolized by a liver enzyme named cytochrome 450 2D6 should be approached with caution because these individuals may develop higher concentrations of Clozaril in the blood that may cause an increase incidence of side effects from the Clozaril.

Discussion is closed
Cancel
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
RSS Expert Activity
233488 tn?1310696703
Blank
Marathon Running Done Over Many Yea...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
233488 tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
748543 tn?1463449675
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank