Prozac, effects of long-term use

I had been using Prozac for the past 10 years, and stopped in 2/01. Started again in 11/01, and noticed nervouses, and flare-up of a rash (open sore, bleeding from itching)on my feet.
Are these known side effects?

How long does it take to "withdraw" from Prozac?

What are the effects of long-term use (is it safe)and does it cause an actual physical dependence in the brain, so that one "needs" it to feel normal??

[Roger Gould, M.D.]

So far all authorities say prozac is safe long term. Regarding the rash, it is a known side effect, and sometimes the drug is discontinued, especially if there is an allergic reaction that effects the lungs. You should definitely consult your doctor about this.

[brad20]

to answer your question about prozacs addiction potential, there is'nt one. prozac, like all SSRI's are not physically addictive and withdraw usually does not occur as in the sense as it would for drugs like xanax, which are physically addictive. i have taken prozac for 6 years without incidence.

[Rayo393]

Hi all. I had been on Prozac for approx. 6 years. I am now off Prozac and trying Effexor. I got off Prozac because it started causing me to stutter, have tremors, have high blood pressure and lose my memory. Since tapering off and coming off it completely these side effects have all diminished except some minor loss of memory at times.

I found out there is a new long term study out on Prozac and it is linked to causing Parkinsons symptoms. Anyone on Prozac for 5 years or more who has ANY of the above symptoms, even just ONE of them, should talk with their doctor and consider changing medications. I am happy to say I am in therapy now with a great counselor and I am looking forward to possibly being able to be rid of antidepressants someday.