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I have been having bouts of nausea and dry heaves for almost four months. I saw a gastroenterologist who did a bunch of tests and diagnosed me with galballder (emptying) problems. I had my galbladeer removed but the symptoms have persisted. My dad read an article about the cumlative effect of anti-deperessants sometimes manifesting as gastrointestinal problems. Is it possible that the Trazodone I'm taking is the problem? I've been taking Trazodone for three years in increasing doses -- started at 50mg/day as an addition to 200 mg/day of Zoloft to help with sleep. I stopped taking Zoloft and incresed my Trazodone to 200 mg/day. In the last month or so I have weaned myself to 150 mg/day in hopes that the symptoms would abate. Any suggestions would be greatly appreciated. Thank you.
Desyrel (Trazodone) is a type of antidepressant that acts by inhibiting serotonin reuptake but is not related to other antidepressants. The average dose given to patients is 200mg.-600mg./day. It is still a question whether Trazodone is as effective as the other antidepressants or as a second-line agent for major depression. The common side effects of Trazodone includes sedation, orthostatic hypotension, nausea, and vomiting. You mentioned you have been taking 200 mg./day and have tapered to 150 mg./day. Side effects may be lessened if the drug is taken in divided doses and with meals. I would still encourage you, however, to discuss with your psychiatrist any changes that you make regarding you medications.
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