yes, this medication can effect his sex drive and cause weight gain. I was on zispin, I was on it for a few years, at first I found it made me very tired all the time and I had difficulty getting up in the mornings, then out of the blue it all done a u-turn, I couldn't get to sleep at all, I used to get restless legs and was irritable from lack of sleep. When I went from Sunday to the Friday without a moments sleep I had to go see my doctor. He took me of them straight away and put me on sertraline instead. I can sleep again now. Its a shame really as zisprin did wonders for my depression. If he has put on 3 stone I would go see your doctor as that in itself can cause severe other problems in the future
good luck
vangellis
yes, this medication can effect his sex drive and cause weight gain. It is an antidepressant medication, and there are others to chose from, so he should definetly have his medication reviewed.