Hi J,
If you Google Remeron and mania you should see the first reference for an RX list page stating this "Mania/hypomania occurred in approximately 0.2% (3/1299 patients) of REMERON®-treated patients in US studies. "
I went to that page but could not find this statement but rxlist will have it somewhere there. Pretty low incidence but possible as it is with many A/D's.
Like you, I had never had a hint of bi polar in my life until, at age 48 I had a 6 week hypomanic episode. I'm sure that was due to mal treatment as the pdoc at that location virtually gave me only one drug, a psychotic for anger.
Nevertheless once you've had an episode that's where they classify you and I have to say I've had 2 small episodes since, in 10 years. I very mild and very enjoyable and was I angry when it stopped? Oh yes. The next though was a rapid cycling nightmare and I wanted no more of hypomania or mania, ever. Lithium did the trick for me luckily, with Effexor, that's been my staple diet for 10 years, in between poop out periods trying some useless new med.
I too don't know what I am as I believe BP was induced in me by the docs failures. But I still have it and have to deal with it don't I? So I can't pretend it isn't likely again as it has proven it does happen. I actually don't mind the diagnosis as it sounds better than depression to so many. Of course they have no idea but it does let you get away with a lot. Just smile at someone you don't like and say "I'm bi polar, you know, manic depressive". And say no more. They tend to freak out so I do have a little fun with it when I'm feeling OK.
The time line of 2 months after starting Remeron is fairly telling isn't it? I'd be asking to switch and try to wean right off before starting the next lot. Check whatever the doc suggests on RX list, a good web site, for side effects before you decide.
Good luck, see you in space sometime, maybe?
Yes anti-depressents worsening mania in a person with bipolar are a possibility. If bipolar is your diagnosis bring this up with your psychiatrist and perhaps they could find a full mood stabilizer that would have an anti-depressent effect if Remeron is potentially worsening mania. Out of all the anti-depressents Wellbutrin is the least likely to worsen mania (but its still a possibility) in people with bipolar so you could ask your psychiatrist about that.