Bupropion or SAMe?

[kgm774]

My husband has been taking Bupropion HSL SR 150mg for a few months and it doesn't seem to be working as well as the Bupropion XL 150mg he was taking for a few years before he was switched because, the pharmacy said, they could not get the Bupropion XL 150mg at that time.  My husband has dementia.  He takes the Bupropion in the morning along with his Aricept and Exforge (for blood pressure).  He gets drowsy right after taking his pills and I think it may be the Bupropion HSL SR causing this.  His neurologist told him the anti-depressant would probably make him "a little more fuzzy in his thinking".  My husband is usually at his best in the morning as far as clear thinking goes.  My question is, would switching him to SAMe still provide the anti-depressive quality that the Bupropion does and would he have less "fuzzy thinking"?  He struggles with his memory and I'm trying to do what is best for him.    

[kgm774]

Thank-you for your reply.  Your info is food for thought.

[Paxiled]

Natural remedies aren't nearly as strong as drugs.  That usually means fewer side effects and safer use, though not always, but natural remedies are basically digested by the body whereas drugs are engineered to make the body act in an unnatural manner.  Generally, natural medicine doesn't use just one remedy, it goes for a holistic approach, but in truth the only way to tell if it will work is to try it.  The problem is, you can't just quit the drug the way you usually can a natural remedy; it has to be tapered off of slowly.  That drug, by the way, usually a stimulating antidepressant, so the fact your husband gets tired afterward just goes to show how everyone reacts differently to things and how impossible it is to predict results.