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I was prescribed Celexa by my GP due to an ongoing health issue causing anxiety and depression. I was told to take it right before bed. I'm not confident the med ever worked for me, but I haven't noticed any issues as it relates to taking it at night. mammo is right, however, you should call your Dr. just to let him/her know you would like to take it a night. Also, I have not seen weight gain with it either.