Does anyone have the opposite effect the medicine makes it worst

Just curious my son seems to do worse on medicine where the medicines take on all the side effects and withdrawl (withdrawal) symptoms but there doesn't seem to be any part of the medicine that makes him feel better that is what he says it doesn't do anything.  He has tried several in a year with all bad results.  Could this just be an individual you cannot medicate and than what do you try.  I have brought my son to the hospital and he's been there twice over a month each time because each time they try a medicine he gets worst and since they really don't know him from anyone else they don't see who he was before he went on medicine.  This happened to him when he tried to got off zyprexa he practically went out of his mind and was very dangerous to himself.  They don't know him and thought this was how he was but after begging them to leave him off the medicine for 2 weeks they noticed a big change in him for one the need to cut himself seemed less necessary.  Is anyone familiar with this?

[ILADVOCATE]

Medications can have side effects and people don't respond to all medications. Best thing is to speak to his psychiatrist find out what his exact diagnosis is and what is available that could help him. There was surely a reason he was diagnosed and they could discuss with you what might work.

[OtisDaMan]

I had prozac as the first medication for clinical depression, ie severe depression. It made me worse in that I went from some psychomotor retardation (as they call it) to virtually unable to breath because of the exertion. Scary. I can well imagine that if this is someone's first experience with depression they may not realise that the worsening effect is possibly due to the medication. The second medication I tried, effexor, improved the situation quite a bit, once the dose was high enough (375mg/day). I have also tried anti-convulsants, one with very bad side-effects, the other with some side-effects that are in need of monitoring because of the potential for heart failure down the track.

Unfortunately it is a bit of a lottery; it depends so much on the individual's liver metabolism, on other medications, age, diet, sensitivity of the nervous system, and so on. One of my friends recently found an older anti-psychotic to be beneficial, but only after moving down through the list as your son is doing.

All the best in the search,

OtisDaMan